Add a couple things to keep in mind
Part rigidity is important . if material flexing in anyway will result in poor finish.
Machine rigidity is important also if there is any flex in the tools this will also cause problems with finish.
I use whiteside spiral up/down and compression cut solid carbide router bits as my end mills.
Speeds and feeds need to be tested and tuned for best results "this can take time" and change if you change brand or type of acrylic.
http://www.cnczone.com/forums/attach...d=288802&stc=1
The picture above shows all parts made and assembled with no polishing or hand work of any type. even threads for fittings are thread milled.