I try to fixture up all of my production parts if I know they will sell enough to make it worthwhile.
Before I had my CNC mill I had an Enco mill/drill. Around 2011 Losi released the SCTE 1/10th scale 4wd RC truck. It was awesome, except for the fact that the cross pins in the differentials were butter soft. They would be worn out in 10 runs or less. I found a prehardened 3mm dowel pin that would fit, but it needed a 3mm x 1.5mm groove cut across each pin. I cut 3500 pins in a fixture one at a time that year. It took Losi 6 months to get their production worked out. I had factory drivers calling me for pins. After I built my CNC I made this fixture to cut 50 at a time:
I also sold a battery tray for that truck that moved the battery back about 1". I made this fixture to hold 10 trays at a time. Ignore the missing Y cover. This is right in the middle of CNC upgrade fever:
This fixture was for a chassis plate for a Kyosho 2wd RC car. The stock ones were pretty brittle. I made a couple hundred of them out of aluminum.
The parts I'm working on now are for high power rocketry and they sell in pretty low volumes. For these I set up soft jaws and cut 1 part at a time. It isn't worth fixturing up at the moment.
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I'm not usually in a big rush so I set up conservative feeds and speeds and let the machine run. Sometimes it's more convenient to have a longer run time. Those chassis plates would run 1-2 hours between tool changes. I'd start a batch, go inside and have dinner, bath the kiddos, put them to bed and the machine would be ready for the next tool.