So I'm trying to figure out which design to go with, I'm not extremely familiar with CNC equipment. I'm wanting to change that by building my first CNC router!

So.. as of right now, I can't tell you the difference between them, except which parts move. Everything else is pretty much fuzzy for me...

Is one design easier to manage (long term) than the other? Does it matter?

What about hybrids, with the table in one axis, and the gantry in the other?