I have chains on X and Y. I think that the accuracy is OK, backlash under control. But the surface finish can show ridges which I believe is due to the cogging effect.
If you do go for chains with a common axle driving both sides of the gantry, I would recommend using a stout shaft (0.5") and support it well at several points between the two drive gears. A reduction (2:1, 3:1) stage would probably be in order as well, especially if you have to go to larger drive gears with the larger shaft. Making sure the two sides of the gantry were 'in-phase' was an issue for my build, so being able to translate the chains relative to the table was important.
Cheers!
Paul Rowntree
Vectric Gadgets, WarpDriver, StandingWave and Topo available at PaulRowntree.weebly.com