If using your machinery on a weekly basis, I would recommend keeping the temp between 50 to 60°F when away. It could be just my imagination, but I don't like the idea of the mechanical strain and relative motion of connectors and circuit boards as they grow and shrink from wide temperature changes. That little bit of slippage induces oxidation of contact surfaces, or induction of crap into the contact area. You just have to work a little bit with the flimsy connectors that are commonplace in modern computers, to appreciate that they work as reliably as they do, because there is nothing robust about the connections.
This comment is not meant to contradict what Karl said, as he wrote that he is basically shut down for months. The number of severe heating/cooling cycles that he would be talking about would therefore be very low.
First you get good, then you get fast. Then grouchiness sets in.
(Note: The opinions expressed in this post are my own and are not necessarily those of CNCzone and its management)