I took the liberty of drawing up a couple ideas real fast. Nothing polished about it, it's just easier to draw it than to try and explain it. Please use all, some, or none of the concepts here, it's up to you .
I used the same 80x80 and 80x120 extrusions. Those are Rexroth size 25 rails and a 25mm ballscrew....simply because that's what I had some drawings of to modify.
To assemble this there would be many countersunk socket head cap screws throughout.
Attachment 446306
Attachment 446308
Attachment 446310
Yellow: Countersunk socket head cap screws bolt this into the T-Slot, leaving the rest of the plate to be drilled and tapped as desired.
Blue: The 80x80 and 80x120 extrusions
Orange: Chip guard....the idea is that any flying chips that can get over this will most likely have enough energy to miss the linear rails and ballscrew....I would be more concerned about getting chips in the ballscrew as the wipers on the linear rails are usually pretty good.
Red: Rest for your Cat Track / Drag Chain....
Hope this helps with your concept design....I really like the concept from LinuxFan of bolting aluminum plate together and filling with epoxy concrete...but I tried to go with the same extrusions you want to use.
Like I said, not trying to steal your thunder, I won't be offended in the least if you go a different direction. Just some ideas.
How long are your ballscrews in your design?