You could bolt a Bridgeport to the wall and it would still work. Staying out of the way of the chips may be a different story. In theory, all I have ever done is shim the base to stop it from rocking.
Isolation: I prefer the floor but I can see there rubber feet are handy, especially to sweep chips from beneath the base. BUT: short story: I shared a small shop in NJ with another machinist. We both had BOSS 9 (R2E4) machines. His was on rubber feet. we were both making microwave aluminum parts, hogging with fast helix 2 flute OSG end mills designed for aluminum work. We both pushed the machines, using identical feed and speeds. My theory is that his rubber feet allowed a greater amplitude of the vibration to get to his CRT. His CRT fell apart inside. Mine did not. The S1STD does not have a CRT so go for it, but at some point you may experience a finish problem from a sympathetic harmonic resonance.
George
(Note: The opinions expressed in this post are my own and are not necessarily those of CNCzone and its management)