Good luck with your build Keith! I get what you mean about 180 degrees for the rails, that's good, but as has been pointed out, thicker material on it's own isn't always the best solution. In some cases it can actually go against you. For example on my import machine, the walls are only 1/2" thick, doesn't sound much, but they have a lot of reinforcing to stop any flexing in any direction. This is important to consider for the sharp changes in direction where momentum can want to twist or "rack" the gantry, Or when it's under load doing a heavy cut and the Z axis wants to twist up and sideways, etc, etc. I can tell you my machine doesn't have any measurable flex at all no matter what i've thrown at it.
I'd go 12mm thick myself, and then use lots of solid bracing. 19-20mm thick means lots of inertia to overcome which can limit your speed, and also really stress the construction.
cheers,
Ian
It's rumoured that everytime someone buys a TB6560 based board, an engineer cries!