Those are pretty extreme accel rates. I think I am running velocities of 80-120 depending on axis and usually accels of 1/10 of that. I have run higher but was suffering a loss of steps during a multiple hole pocketing routine when using CamBam. I can get it to repeat the error. I can even identify the line where it goes askew but there is no reason. The speeds aren't too fast and it will skip during an air cut too.
I broke and will continue to break end mills and parts in my journey. It is the way I learn unfortunately. Better than not learning at all, a little more expensive though. It is hard to listen to a machine as it cuts properly. Many times to me or other noobs or novices the sounds are very counterintuitive. The more is better approach is not always the answer here. I used to like high rpms in the spindle and if feed rate was proportional it is a good thing most likely. I have found trying to slow the spindle speed down works better because my tendency is to go too high and burn up the tool. Me and the local metal recycler are good friends now.
A lazy man does it twice.