Nice CAD work! To critique this design I'd have to echo other people's comments because they are right of course.
In that size machine you will get huge rigidity gains from going to fixed gantry and moving table. I'll give my input having built almost exactly the machine you described (by specs) but done as a moving table build.
My design uses a "L shaped gantry plate" bolted directly to the base plate but at 90'. The L shape plate cannot flex at all trapezoidally giving massive rigidity from one cheap part. I see you are in Australia, you can ring one of the big aluminium suppliers to order the 2 main plates, they will even cut to size and cut the L shape for you on their table saw.
Once you have the gantry and base plate rock solid that can't move relative to each other, it's pretty easy to make the 3 axes pretty solid as you have flat rigid plates to bolt the X and Y directly to, and Z is the only axis mounted on another axis so you just need to keep the geometry good so you don't amplify slop.
I used plastic linear bearings as they are "snug" and it's more like a milling machine bedways; the precision of no slop but best at slower speeds. On a 400x300mm machine speed is not a problem!
You can see my little machine here; http://www.cnczone.com/forums/cnc_wo...ll_router.html and you are welcome to copy any ideas ie the "L shaped fixed gantry plate".