I don't know if there are any other settings in the ESS plugin, as I've never used one.
Maybe try adding some noise filtering on the probe input?
Make sure you have the latest plugin, and version 3.043.062.
https://www.warp9td.com/files/Plugin...0220_u4f1L.zip
I loaded your .xml, and don't see anything out of the ordinary.
The fact that it's random may point to something in your configuration or installation?
The only other suggestion would be to create a new profile from scratch, and only set up the bare minimum for testing the auto zero.
Sorry, but I don't have any other suggestions.
If you can't get it to work, and would like a refund, send me an email.