Hi,
Check an axis by entering a set distance move into the MDI eg "g01 f10 x50" (metric)
the feed rate should be set low enough to visually inspect the drivetrain looking at the coupling etc.
Mark the start point and expected endpoint, if the result does not correspond then either the drive is loosing pulses or the mechanics are amiss.
Try turning the motors by hand (without power) and feel for binding or friction.
Further action will require some electrical diagnostic equipment... what are your capabilities in this area?
Andrew